[RA-03] Lobolar neoplasm: how to define and diagnose?

The term "lobolar neoplasia (LN)" is defined by the WHO Classification of Breast Tumour, 5th edition, 2019 as the entire spectrum of atypical epithelial lesions originating in the terminal duct lobolar unit and characterised by a proliferation of generally small, non-cohesive monomorphic cells, with or without pagetoid involvement of terminal ducts. Atypical lobolar neoplasia (ALH) and lobolar carcinoma in situ (LCIS) are separated by the extension of the disease. ...